Universal Sans

Daniel recently clued me in to Universal Sans; a highly customizable typeface complete with web interface to dial in your specifics. You set everything from the x-height to the ink trap style to the punctuation style to make it your own. There are certainly some limitations - you aren't drawing a typeface from scratch! - but it's a very nice way to make a unique look within some very respectable confines.

If nothing else, just go play around with the configuration options. It's surprisingly fun.