Jason Santa Maria makes a great argument for A Real Web Design Application to go into development. Maybe Adobe can take on the task. Maybe some other third unknown party. Whoever it is, his stance is that of all the applications available to web designers today there isn't really one that really captures the process of proper web design. Type engines are currently off, grid structures need to be more flexible and insight into different rendering schemes are completely neglected.

Could an application built on Webkit help solve this problem? Possibly. Whatever the solution is, I fully support such an endeavor and would love a proper Web Design Application - along the lines of what he describes - to exist. Someone get a Kickstarter going.